According to the professor, the esophageal ultrasound-guided minimally invasive occlusion technique is simple and easy to perform, and there is no risk of endovascular injury. It is basically not limited by the patient’s age and weight, and is suitable for atrial septal defects, ventricular septal defects, patent ductus arteriosus, residual fistulas of ventricular defects, and mosaic techniques for complex heart disease. This technique has been used in patients with perimembranous restrictive ventricular defects between 5 and 12 mm in diameter, without other co-morbidities, and without pulmonary hypertension. At this stage, the following conditions are contraindicated: those with significant aortic valve prolapse, large ventricular septal defects in newborns or small infants with moderate or higher pulmonary hypertension, non-restricted ventricular septal defects with large diameters and poorly defined borders, and sub-stem ventricular septal defects.