1.With symptoms of blood in the naked eye or back pain, go to the hospital immediately for ultrasound examination of the bladder, ureter and kidney. 2.B ultrasound reveals bladder occupancy, further examination of pelvic enhancement CT and cystoscopy should be performed. 3.Cystoscopy clearly sees bladder tumor, combined with pelvic CT scan results, if the tumor grows superficially, first minimally invasive TURBT (transurethral bladder tumor electrosurgery). 4. After TURBT, according to the pathological results of the resected specimen, if the tumor is low grade, solitary and less than 3cm, bladder perfusion chemotherapy can be started 1 week after TURBT. If there is no recurrence, then start bladder infusion chemotherapy every 2 weeks *6 times, then review cystoscopy, if there is no recurrence, then change to bladder infusion chemotherapy every 4 weeks *18 times, during which review cystoscopy every 3 months. every 6 months after 2 years, then review cystoscopy every 6 months. after 5 years, review cystoscopy once a year. 6, If the pathology after TURBT is high-grade tumor, or more than 3 tumors, or tumors larger than 3 cm, you need to TURBT again after 4-8 weeks, and then start the bladder perfusion chemotherapy as mentioned above for 2 years. 7. If tumor recurrence is found on cystoscopic review during follow-up, it should be re-evaluated based on cystoscopy and pelvic CT, and if it is still superficial, minimally invasive TURBT can be performed again. After surgery, another bladder perfusion chemotherapy drug should be replaced to continue bladder perfusion chemotherapy. 8. If the tumor has infiltrated the muscle layer of bladder wall or broken through the bladder wall, systemic evaluation and examination are needed to exclude distant metastases, such as lung, bone, lymph node metastases, and patients without metastases can undergo radical bladder resection + urinary diversion surgery. 9. There are 3 main types of urinary diversion surgery: in situ ileal neobladder, ileal output tract, and ureteral skin stoma. In situ ileal neobladder does not require wearing a urine collection bag after surgery, and patients can still urinate from the original urethra. Ileal output tract and ureteral skin stoma require a urinary bag. 10. Follow-up visits after radical cystectomy are usually every 3-6 months. Follow-up visits include blood draws for liver and kidney function, blood count, electrolytes, abdominal ultrasound, pelvic enhancement CT, and plain CT or x-ray of the lungs. 11.After radical cystectomy surgery, if the pathology suggests very high malignancy of bladder cancer with high chance of recurrence and metastasis, adjuvant chemotherapy is needed after surgery, usually 4-6 cycles.