Double eyelid jumping may be due to eye fatigue, lack of sleep and other physiological factors, but also due to facial muscle spasm, Meige syndrome and other conditions. 1. Physiological factors: Usually, the patient’s life habits are poor, resulting in excessive eye use, eye fatigue, double eyelid jumping will often occur. Patients who do not have enough sleep can also be induced by double eyelid jumping. The above situations are normal physiological phenomena, patients can recover by themselves after proper rest and improved sleep. 2. Facial muscle twitching: mostly due to the pressure of blood vessels in the bridge cerebellar angle area on the root of the facial nerve, but also related to tumors, inflammation, facial neuritis and other factors. Patients often appear on one side of the facial muscles rhythmic, paroxysmal twitching, and the onset of the early stage can also appear orbicularis oculi muscle intermittent twitching, can be manifested as double eyelid jumping. At the same time, some patients may also be accompanied by facial pain, fatigue, agitation and so on. 3. Meige syndrome: the cause of primary Meige syndrome is not clear, while secondary Meige syndrome is related to trauma, psychology, drugs and other factors. Patients often have symptoms of bilateral blepharospasm, which can also be manifested as eyelid weakness, eyelid ptosis, etc., while some patients can also be accompanied by eyelid irritation, dry eyes, photophobia and other phenomena. It is recommended that patients with symptoms of double eyelid throbbing should clarify the cause of the condition in time and follow the doctor’s instructions for standardized treatment.