Trigeminal neuralgia is the most common clinical disease, mostly occurs in the middle-aged and elderly people, the pain attack like cutting, burning, electric shock-like sensation, so many patients dare not speak, eat, drink, known as the “world’s first pain”. The trigeminal neuralgia treatment effect is often affected by the fact that some patients are in a hurry to seek treatment, so we remind the majority of trigeminal neuralgia patients should avoid three major misconceptions in the treatment. Myth No. 1: Mistaking trigeminal neuralgia for toothache and pulling teeth because of the similarity between the painful parts of trigeminal neuralgia and toothache, it is very easy to be confused, thinking that it is a toothache and that tooth extraction can relieve the pain, without knowing that it delays the timely and correct diagnosis and treatment. Trigeminal neuralgia is characterized by recurrent episodes of severe pain in the facial areas such as the lips, corners of the mouth, nose, palate or oral mucosa. Therefore, early mild trigeminal neuralgia or atypical trigeminal neuralgia is often mistaken for toothache, migraine, sinusitis or other stomatological or quintuplegia diseases, and patients even blindly go to tooth extraction, thinking that the root of the disease can be removed, which is actually a big mistake. Many trigeminal neuralgia patients suffer from trigeminal neuralgia for many years, and after many treatments are ineffective, as the saying goes, they often mistakenly believe in some so-called “partial prescriptions and ancestral secret recipes” for the treatment of trigeminal neuralgia, and as a result, the money is not less spent, and the pain is not reduced, but leads to various complications. The result is that money is not spent and pain is not reduced, but leads to a variety of complications, resulting in lifelong regret. When it comes to surgical treatment, some patients are still worried and afraid, thinking that surgery requires opening the skull and making an incision in the brain. In fact, microvascular decompression surgery for trigeminal neuralgia is a very mature surgical technique that has been clinically used for more than 60 years. Moreover, the surgery is not performed inside the brain, but in the subarachnoid space between the brain tissue and the skull, so the surgical risk is very low. Currently, microvascular decompression surgery is an internationally reliable method for the eradication of trigeminal neuralgia. Of course, not all patients must undergo microvascular decompression surgery. The general treatment principle is: for patients with relatively mild pain, we first apply medication, and consider surgery only when medication is ineffective or when the side effects of medication are not tolerated. For elderly patients, especially those whose general condition is not suitable for general anesthesia, it is recommended that radiofrequency treatment is preferred when drug treatment is ineffective. For patients with severe pain that seriously affects their lives, microvascular decompression surgery should be preferred.