Stone-obstructive jaundice medication is effective, but cannot solve the underlying problem. The obstruction caused by bile duct stones and the obstruction of enterohepatic circulation lead to the increase of blood bilirubin and the yellowing of the sclera and the skin all over the body, which can be reduced a little bit by medication but is easy to be repeated. Whether it is extrahepatic bile duct stones or intrahepatic bile duct stones, as long as they cause obstruction, if there is no contraindication to surgery, surgical treatment is recommended. Medications can only temporarily control the increase in bilirubin or promote the excretion of bilirubin, but cannot achieve a cure. There are several ways to treat obstruction caused by stones, depending on the patient’s condition. When obstructive jaundice occurs, it is also necessary to pay attention to water electrolyte and acid-base balance disorders, liver protection, anti-infection and other treatments, so it is recommended to consult a doctor in time.