The manifestations of liver damage caused by anti-tuberculosis drugs include: hepatic adaptive reaction, acute hepatitis or hepatocellular injury, acute cholestasis, and hypersensitivity reaction. 1. Hepatic adaptive response: after taking certain anti-tuberculosis drugs, the patient triggers the adaptive response of the liver, and transient transaminase elevation occurs, but there are no clinical symptoms. 2. Acute hepatitis or hepatocellular injury: Mild manifestations include gastrointestinal symptoms such as epigastric discomfort, nausea and anorexia. In severe cases, there will be fever, yellow staining of skin or sclera, deepening of urine color and other symptoms. 3. Acute cholestasis: mild manifestations of loss of appetite, abdominal distension, nausea, etc., and severe manifestations of epigastric pain, fever, jaundice, itchy skin and other symptoms. 4. Hypersensitivity reaction: some anti-tuberculosis drugs can induce hypersensitivity reaction of the body, and then appear in addition to the manifestations of liver injury, there will be fever, fatigue, muscle pain, rash, superficial lymph node enlargement of the symptoms. It is recommended that tuberculosis patients taking anti-tuberculosis drugs for the process of anti-tuberculosis treatment, should closely monitor liver function, if the above symptoms, should promptly follow the doctor’s instructions to adjust the drug or dose, to improve the above symptoms.