Since the age, physical condition and degree of disease vary from patient to patient, there is no specific drug for trigeminal neuralgia, and the drug treatment plan that can effectively improve the disease should be formulated according to the patient’s own situation. At present, the most important drugs for trigeminal neuralgia are carbamazepine and oxcarbazepine, etc. Patients should start with small doses under the guidance of doctors and gradually increase the dosage until the condition can be controlled. At the same time, as the condition worsens and the duration of medication increases, patients may develop drug resistance, that is, the current medication cannot effectively relieve trigeminal neuralgia, so it is necessary to combine other drugs together, such as gabapentin and pregabalin. However, it should be noted that all drugs for trigeminal neuralgia have certain side effects, for example, carbamazepine can cause some damage to the liver when taken for a long time, and patients need to have their liver function checked regularly, so they also need to combine with nerve-nourishing drugs such as glutathione and vitamin B1. While taking medications, patients can also combine acupuncture, physical therapy, radiofrequency, etc. for comprehensive treatment. In addition, since drug treatment for trigeminal neuralgia is mostly applicable to the early stage, along with the prolongation of the disease, the effect of drug treatment usually gradually decreases, and surgical treatment can be considered at this time, such as partial severance of trigeminal sensory roots, Gamma knife treatment, trigeminal nerve microvascular decompression, etc.