It is difficult to treat anal fistula solely through the use of medication. Anal fistula is treated by surgically cutting the fistula open, in addition to preventing constipation, warm water sitz baths, and oral antibiotics to control infection. Anal fistula is mostly secondary to perianal abscess, which is a disease that results in the formation of granulomatous ducts around the anal canal or rectum due to infection. The disease is often prolonged or recurrent, and the treatment should be carried out through surgery such as fistulotomy, hanging thread therapy, and anal fistulotomy, through which the fistula can be incised or excised to form an open wound in order to treat anal fistula. In addition, medications such as lactulose can be used to improve constipation to reduce the irritation of stool on the fistula, potassium permanganate solution can be used in sitz baths to clean the local area, and medications such as cefixime and metronidazole can be taken orally to fight infection. If the diagnosis is anal fistula, please follow the doctor’s instructions for treatment.