High levels of urinary porphyrins in the urine are due to porphyria. Porphyria is a disorder of porphyrin metabolism characterized by increased excretion of porphyrins and porphyrin precursors in the urine and feces. Porphyria is a congenital disorder caused by a deficiency of various enzymes related to heme synthesis and has a family history of occurrence. What are the symptoms that can be easily confused? When the disease has abdominal pain, it should be differentiated from acute abdominal disease. When neuropsychiatric symptoms are present, it should be differentiated from pellagra, scleroderma and dermatomyositis. When the disease is positive for uroporphyrinogen, it should be distinguished from symptomatic porphyriuria caused by lead, gold, arsenic, alcohol, benzene, carbon tetrachloride poisoning, and aplastic anemia, substantial liver disease, connective tissue disease, Hodgkin’s disease, leukemia, etc. 1, acute abdomen Acute abdomen is a general term for acute abdominal disorders. Common acute abdominal disorders include: acute appendicitis, acute perforation of ulcer disease, acute intestinal obstruction, acute biliary tract infection and cholelithiasis, acute pancreatitis, abdominal trauma, urinary stones and ruptured ectopic pregnancy. In addition, certain systemic or other systemic diseases, such as hematoporphyria, hypokalemia, septicemia, spinal trauma, or spinal cord disease, may also present with clinical manifestations similar to those of acute abdomen. The first site of occurrence may be the primary site of the lesion. 2, scleroderma Scleroderma (scleroderma), is a connective tissue disease characterized by limited or diffuse fibrosis, sclerosis and atrophy of the skin and connective tissue of internal organs. Some patients only have skin sclerosis, which is called limited scleroderma, while some patients also have fibrosis and sclerosis of the heart, lungs, gastrointestinal and kidney internal organs, which is called systemic scleroderma and is often serious and has a poor prognosis. It is most common in women of childbearing age, and it can also occur in children and the elderly, and there are reports of more scleroderma in miners and workers exposed to silicon. Carbon tetrachloride (carbontetrachloride, CCL4), also known as tetrachloromethane, is a colorless, transparent, fat-soluble, oily liquid with a slightly sweet odor similar to chloroform, non-flammable and volatile. It is a recognized hepatotoxic substance. Acute carbon tetrachloride poisoning is mostly caused by inhalation of its high concentration vapor during production work, with central anesthetic symptoms and liver and kidney damage as the main features. 4, aplastic anemia Aplastic anemia, referred to as reblastosis, is a group of bone marrow dysfunction caused by a variety of etiologies, the main manifestation of the syndrome of whole blood cell reduction. The exact cause is not yet clear, but it is known that the onset of aplastic anemia is related to chemical drugs, radiation, viral infection and genetic factors. According to a survey conducted in 21 provinces (cities) and autonomous regions in China, the annual incidence rate is 0.74/100,000 population, which is significantly lower than that of leukemia; the incidence rate of chronic reoccurrence is 0.60/100,000 population and that of acute reoccurrence is 0.14/100,000 population. The incidence is slightly higher in males than in females. The disease is divided into acute and chronic reoccurrence according to its onset and duration.