Plantar warts are caused by human papillomavirus infection and are found on the heel, the front of the foot or in the pressured area between the toes, mainly as yellowish or maroon patches. In terms of the application of drugs, as much as possible for the human papillomavirus and choose, common topical drugs are vincristine ointment, warts and allergies ointment, aciclovir ointment, interferon gel, imiquimod cream, fluorouracil ointment, salicylic acid solution, zebularin, etc., oral drugs are zinc sulfate, cimetidine and other immunomodulators. All these drugs can be applied with relatively good effect. It is recommended to use the drugs under the guidance of doctors and avoid self-medication. However, if the application of ointment is not effective, it is recommended to choose physical therapy, such as the application of cold nitrogen or microwave treatment.