Many babies mothers and fathers do not know what are the high-risk factors, what kind of children are high-risk children, here we come to learn about high-risk factors and high-risk children: high-risk factors 1, environmental factors: misuse of drugs, poisons, radiation, electromagnetic, radiation, etc.. 2, maternal factors: ① high maternal age; ② gestational hypertension and diabetes; ③ cholestasis (ICP); ④ intrauterine infection; ⑤ multiple pregnancy; ⑥ preeclampsia; ⑦ amniotic fluid, amniotic fluid contamination; ⑧ intrauterine distress. ⑨ Exposure to radiation, harmful chemicals or drugs during pregnancy, infection during pregnancy (TORCH). Chronic diseases during pregnancy, etc. 3, the placenta, umbilical cord factors: ① aging of the placenta; ② abnormal placenta; ③ placenta praevia; ④ placental abruption; ⑤ umbilical cord anomalies; ⑥ umbilical cord around the neck and so on. Fetal and neonatal factors: ① preterm delivery; ② pathological jaundice; ③ ischemic-hypoxic encephalopathy; ④ intracranial hemorrhage; ⑤ low-birth-weight babies (especially babies younger than the gestational age); ⑥ in vitro fertilization and so on. Genetic factors: ① family history; ② chromosomal abnormalities; ③ gene mutation, deletion and other genetic diseases. 6.Endocrine factors: e.g. low thyroid hormone. 7. Metabolic factors: hyperammonemia, metabolic diseases such as amino acids, fatty acids, organic acids, etc. High-risk babies Broadly speaking, it refers to a special group of babies with various risk factors that are unfavorable to the growth and development of the fetus and the baby during the mother’s pregnancy, delivery, and the neonatal period, accounting for about 60% of the total number of newborn babies. Narrow sense: It refers to the children who receive supervision and treatment in NICU. Often, foreign high-risk infants refer to this group, such as premature infants with birth weight less than 1500 grams. Maternal and child management law put forward to improve the quality of the birth population, to ensure the safety of children’s lives, early detection and early management of early intervention, so our babies mothers and fathers need to pay special attention to our babies, if early detection, early intervention can be made, the general prognosis is relatively good.