The principle of interferon treatment for warts is to utilize interferon with broad-spectrum antiviral, enhanced immunity, and anti-cell proliferation effects. 1. Broad-spectrum anti-virus: warts are a sexually transmitted disease caused by human papillomavirus infection. Interferon does not directly kill or inhibit the virus, but mainly through the cell surface receptor role of the cell to produce antiviral proteins, so as to inhibit the replication of the virus; so as to achieve the purpose of treatment of the disease. 2. Enhancement of immune function: Interferon is a group of active proteins with multiple functions, mainly glycoproteins, produced by leukocytes, monocytes and lymphocytes, which can enhance the vitality of natural killer cells (NK cells), macrophages and T-lymphocytes, thus playing the role of immune regulation and enhancing the ability of anti-virus. 3. Anti-cell proliferation effect: directly prolong the cell proliferation cycle through enzyme induction; inhibit cell proliferation by reducing oncogenes and mitotic activity. Currently, IFNα-2a, IFNα-2b and IFN-γ are more commonly used in clinical practice. IFN can be applied alone or as a treatment after removal of warts by cryosurgery, carbon dioxide laser, electrocautery, surgical treatments and traditional therapies such as onychomycosis resin. Of course, the specific treatment requires further medical consultation and standardized treatment under the guidance of a doctor.