Oral acromegaly can usually be cured. Usually oral acromegaly refers to the acromegaly that occurs in the oral mucosa, which is produced in the case of damage caused by HPV infection, and the virus usually lurks in the mucosa and under the skin. Once the patient’s resistance drops or when local hygiene is poor, it may lead to recurrence. Usually its treatment mainly consists of removing the warts and preventing recurrence. Usually patients should first remove the warts by microwave, laser, freezing and surgery, and then help to remove the HPV virus and promote the warts to subside by improving the immunity of the overall and local mucous membranes. In general, patients can be cured of oral acromegaly by these two methods. Patients are advised to seek prompt medical attention if they develop oral acromegaly to avoid delays.