Upstairs chest pain may be caused by coronary heart disease, emphysema and pleurisy. 1. Coronary heart disease: coronary angina is caused by insufficient blood supply to the coronary arteries and rapid transient ischemia and hypoxia of the myocardium, which is mainly manifested as paroxysmal chest pain or chest tightness. The most common type of coronary heart disease is chest tightness and chest pain when fatigue, especially when climbing stairs, which will be relieved soon after resting, which is the characteristic of exertion angina. 2. Emphysema: When emphysema patients have chest pain, they should first consider whether it is complicated by spontaneous pneumothorax. Spontaneous pneumothorax is the most common complication of emphysema because pleural rupture can lead to the symptom of chest tightness and pain, especially when taking a deep breath or coughing while climbing stairs. 3. Pleurisy: especially when deep breathing or coughing, chest pain is aggravated, pleurisy causes chest tightness pain upstairs mainly due to the friction between the chest wall and visceral layer. Patients who appear upstairs chest pain symptoms, should go to the hospital in time for relevant examination, clear diagnosis and symptomatic treatment.