Fat grains generally do not fall off naturally, and can be removed by applying retinoic acid, laser treatment, surgical treatment, etc. As they are benign lesions, they do not require special treatment. Fat grains are benign skin lesions that are usually asymptomatic and do not require treatment. If there is any obvious discomfort or if the lesions are more severe, the fat grains caused by milia with more lesions can be treated by applying retinoic acid. In addition, the fat grains caused by sweat duct tumors and milia can also be treated by laser; those caused by milia can be removed by needle picking; and those caused by larger rashes can also be removed by surgery. Fat grains that do not affect the appearance of the skin can be left untreated, but if they affect the appearance of the skin, or if the skin lesions are large, they can be treated with medication or a suitable treatment program under the guidance of a doctor.