HPV is the human papilloma virus, and plantar warts on the feet are infected with the human papilloma virus. Plantar warts are benign growths of the foot and plantar area caused by human papilloma virus infection, and are found on the heel and the front of the foot and plantar area. Therefore, plantar warts on the feet are indeed infected with human papilloma virus. The patient mainly manifests the symptoms of hyperkeratosis, rough plate, papules and nodules on the pressurized area of the foot, and some patients also have pain. Plantar warts can also be induced by prolonged friction on the feet, trauma, sweaty feet, and low immunity. Laser treatment, liquid nitrogen cryotherapy and electrocautery can be used to eliminate warts. In addition, topical salicylic acid can also be used as prescribed by the doctor, which promotes the peeling effect of the epidermis. Topical imiquimod ointment can also be used, which has an immunomodulatory effect. Plantar warts on the feet are indeed infected with the human papilloma virus, and patients are advised to use medication under medical supervision.