The treatment of urethral acromegaly includes local medication, physical therapy, and surgery. 1. local drug treatment: including onychomycosis, imiquimod, containing opium, etc., drug clinical treatment data is relatively lack of, and need to be used under the guidance of the doctor. 2. Physical therapy (1) Laser therapy: CO2 laser treatment, applicable to multiple warts. (2) cryotherapy: liquid nitrogen treatment, applicable to warts smaller or less extensive. (3) electrocautery: electric knife or electric needle treatment, suitable for warts larger. (4) microwave: high-frequency electromagnetic waves can produce coagulation, thermal effect and non-thermal effect of the triple role, the recent efficacy is good. (5) photodynamic therapy: safe, effective, low recurrence rate and good patient tolerance. 4. Surgical treatment: suitable for huge warts. The urethral condyloma acuminatum treatment is more, the patient should not self-medication, should go to the hospital in time, under the guidance of the doctor standardized treatment.