It should be said that the surest measure to eliminate the risk of genital HPV infection is to avoid any genital contact with another person, which seems impossible! It should be said that for sexually active women, maintaining a long-term, regular relationship with one’s sexual partner is an effective measure for maximizing the prevention of genital HPV infection. However, even so it is still difficult to clarify whether a sexual partner has been previously infected. It is unclear how useful condoms are in preventing HPV infection, as areas not covered by condoms can be infected by the virus. Although the role of condoms in preventing HPV infection is unclear, it seems that the simplest and most effective measure at this time is to wear condoms. I should say that the protective effect of wearing condoms is more beneficial to women! Studies have found that condom use does lead to a decrease in the incidence of cervical cancer, the main cause of which is HPV infection. The FDA has approved two vaccines against HPV infection, Gardasil® and Cervarix®, which are effective in preventing persistent infection with HPV types 16 and 18, the two types of HPV that cause 70% of cervical cancers. In addition, Gardasil also protects against both HPV types 6 and 11, which are associated with almost all genital warts (90%). There are some early findings that Cervarix also provides partial protection against other types of HPV that may cause cancer.