There are more reasons for unclean menstruation after egg collection, and the common ones are endocrine disorders, dysfunctional uterine bleeding, endometrial thickening, endometrial polyps, endometriosis, submucosal fibroids, and so on, which need to be clearly diagnosed and treated accordingly. Common causes and treatments 1, endocrine disorders: common in estrogen and progesterone secretion abnormalities, can appear menstrual cycle disorders, irregular vaginal bleeding and other symptoms, should check the sex hormone six clear diagnosis, the treatment can follow the doctor’s instructions to use phenol sulfonyl ethylamine capsules. At the same time, we should pay attention to personal hygiene, abstain from sex, eat more nutritious, easy to digest food, avoid spicy, stimulating, cold food, etc.; 2, dysfunctional uterine bleeding: caused by neuroendocrine disorders, manifested as irregular uterine bleeding, blood volume is sometimes more or less, or suddenly increased, excessive blood loss can cause anemia. Diagnostic curettage, ultrasound, hysteroscopy can be done to confirm the diagnosis, and the use of progesterone and antiemetic drugs, such as dydrogesterone, tranexamic acid, etc., as prescribed by the doctor, and in severe cases, curettage can be done to stop the bleeding; 3. Thickening of uterine lining: it often manifests itself as irregular bleeding from the vagina or amenorrhea for a period of time followed by a prolonged period of heavy bleeding from the vagina. Should go to the hospital to do endometrial histological examination to confirm the diagnosis, the methods of sampling, including endometrial biopsy, dilatation of the uterus scraping, negative pressure suction, hysteroscopy and so on. Ovulation drugs and progesterone drugs can be used as prescribed by the doctor, or surgical treatment can be chosen; 4, endometrial polyps: manifested as excessive menstruation and prolongation of menstrual period, which can be accompanied by abdominal pain, leukorrhea and other manifestations. They should go to the hospital for gynecological examination, vaginal ultrasound and hysteroscopy, and can be treated by hysteroscopic electrosurgery. If they cannot be eradicated or recur frequently, total hysterectomy can be considered; 5. Endometriosis: it can manifest as heavy menstruation or cycle disorders, accompanied by dysmenorrhea, pain during sexual intercourse, etc. It is recommended to do CA125 (Cancer Antigen 125) measurement, ultrasound, MRI and laparoscopy to confirm the diagnosis, and medication can be used as required to treat it. Medications can be used as prescribed by doctors, commonly used non-steroidal anti-inflammatory drugs and hormonal drugs, and conservative or semi-radical surgery can be chosen for surgical treatment; 6. Submucous fibroid of uterus: it can cause increased menstrual flow and prolongation of menstruation, and it can lead to secondary anemia if the patient has long time of excessive menstruation. Ultrasonography and hysteroscopy should be performed to confirm the diagnosis, and hysteroscopic myomectomy or hysterectomy can be chosen as the treatment. Precautions after egg extraction should pay attention to rest, avoid strenuous exercise and sexual life for half a month, eat light and easy to digest food. Use antibiotics, such as azithromycin, to prevent infection, and use progesterone for luteal support from the day of egg retrieval. Those with a large number of eggs should pay attention to changes in urine output, keeping the urine output at about 2000mL per day, and can drink more orange juice, watermelon juice and other diuretics.