Cold and cough is mainly caused by viral causes, and there is no so-called the most effective treatment drugs, mainly symptomatic drugs and cause-specific drugs, often can be used to relieve cough and phlegm; if the combination of bacterial infections, you can use anti-infective drugs to treat. 1. Cough and phlegm medicines: for coughing up phlegm or phlegm difficult to cough out symptoms, can use acetylcysteine, aminobromine and other expectorants to resolve phlegm. For patients with severe cough or dry cough, cough suppressants such as dextromethorphan or pentoxyverine can be used to relieve cough. 2. Anti-infective drugs: Colds usually refer to upper respiratory tract infections, for viral infections caused by colds and coughs usually do not need to use anti-viral drugs to treat. For bacterial infections that lead to colds and coughs, there are often symptoms of coughing up yellow pus and sputum, and antibiotics such as amoxicillin and cephradine can be used to fight the infection. 3. Other: in the late stage of cold, cough is caused by airway hyperresponsiveness, need to pay attention to reduce airway hyperresponsiveness, can apply antihistamines (such as benadryl), also need to pay attention to the possibility of cold-induced cough variant asthma, the need for inhalation of bronchodilators (such as salbutamol) and glucocorticoids (such as budesonide) treatment. Colds and coughs are usually self-limiting and can be relieved by general treatment such as drinking plenty of fluids, resting and keeping warm. If the symptoms are severe, medication can be used under the supervision of a doctor. The medication should be used in strict accordance with the doctor’s instructions, and if there is any discomfort after using the medication, the patient should consult a doctor promptly.