Antibiotics are a class of secondary metabolites produced by microorganisms (including bacteria, fungi, and actinomycetes) or higher plants and animals in the course of their lives that have anti-pathogenic or other activity and can interfere with the developmental functions of other living cells. The antibiotics that are now commonly used in clinical practice are extracts from microbial culture fluids and chemically synthesized or semi-synthesized compounds. There are no less than 10,000 known natural antibiotics. Uses: Antibiotics used to be called antimicrobials, but in fact it can not only kill bacteria and other disease-causing microorganisms such as mycobacteria, mycoplasma, chlamydia also have a good inhibitory and killing effect, in recent years usually renamed antimicrobials as antibiotics. Antibiotics can be a substance produced during the growth and reproduction of certain microorganisms, used to cure the disease in addition to the direct extraction of antibiotics; there are completely synthetic or partially synthetic. In layman’s terms, antibiotics are drugs used to treat various bacterial infections or to inhibit infections by disease-causing microorganisms. Toxic reactions: 1. Toxic reactions of the nervous system; aminoglycosides damage the eighth pair of brain nerves, causing tinnitus, vertigo, deafness; high-dose penicillin G or semi-synthetic penicillin or cause neuromuscular blockade, manifested as respiratory depression or even respiratory arrest. Chloramphenicol and cycloserine cause psychotic reactions, etc.; 2. Toxic reactions of hematopoietic system; chloramphenicol can cause repletion anemia; chloramphenicol, ampicillin, streptomycin and neomycin can sometimes cause granulocyte deficiency. Gastrointestinal reactions: oral antibiotics can cause stomach discomfort, such as nausea, vomiting, epigastric fullness and loss of appetite. Among the tetracyclines, especially chlortetracycline, doxycycline and dimethyltetracycline are significant. Among the macrolides, erythromycin is the most serious, while methomycin and spiramycin are less serious. Tetracyclines and rifampicin can occasionally cause gastric ulcers; 5, long-term use of antibiotics can lead to the wrong kill the body’s normal probiotic flora, resulting in intestinal disorders, which cause a variety of intestinal abnormalities and adverse reactions. Can use gold bifidobacterium (bifidobacterium lactobacillus triplex live tablets) to supplement the normal probiotic flora in the body wrongly killed by antibiotics, to avoid a variety of intestinal dysbiosis caused by taking antibiotics intestinal abnormalities and adverse reactions; 6, antibiotics can cause dysbiosis, causing vitamin B and K deficiency; can also cause secondary infections, such as pseudomembranous enteritis, acute hemorrhagic enteritis, Candida infection. Pseudomembranous enteritis caused by lincomycin and clindamycin is the most common, followed by vanguardycin IV and V. Acute hemorrhagic enteritis is mainly caused by semi-synthetic penicillin, with ampicillin causing the most chances. In addition, long-term oral high-dose neomycin and application of kanamycin cause degenerative changes in the intestinal mucosa, leading to malabsorption syndrome, causing diarrhea and long-term weight gain in infants, which should be preoccupied. A few people with antibiotics cause anal itching and perianal erosion, the symptoms can disappear after stopping the drug; 7, antibiotic allergic reactions are generally divided into anaphylaxis, serum sickness-type reactions, drug fever, rash, angioneurotic edema and allergic myocardial damage; 8, antibiotic sequelae refers to the after-effects of discontinuing the drug, such as permanent deafness caused by streptotoxin. Many chemotherapeutic drugs can cause “triptogenic” effects. The rate of teratogenicity of rifampicin is 4,3%, chloramphenicol, ashwagandha and some antitumor antibiotics have mutagenic and carcinogenic effects. After using antibiotics, it is best to supplement the probiotics children use antibiotics, the impact on the gastrointestinal tract is greater. This is because under normal conditions the human intestine hosts many species of bacteria that make up the normal flora. 90% of the normal flora are resident bacteria, mainly E. coli, Bifidobacterium, etc.; 10% are passerine bacteria, including E. coli, Aspergillus, Pseudomonas aeruginosa and Staphylococcus, etc. The beneficial bacteria and harmful bacteria in the intestinal tract are mutually restrained and coordinated to maintain the micro-ecological balance, but also to block the invasion of foreign attack bacteria, thus maintaining the health of the body. But antibiotics do not grow eyes like people, sterilization often good and bad through kill. As sensitive bacteria in the normal flora are inhibited or killed, drug-resistant bacteria such as staphylococcus lose resistance and restraint from other bacteria and take advantage of the opportunity to multiply, causing disruption of the intestinal bacterial flora. The child also suffers from loss of appetite and decreased immunity. Infant experts remind parents not to panic when their children have the above symptoms, but to take probiotics to regulate the intestinal flora of their children and restore the ecological balance of the intestinal flora.