This beautiful picture “Thousand Hands Guanyin” was the grand prize for the most beautiful dance at the CCTV Spring Festival Gala in 2005. While people marvel at the beauty and touching nature of the dance, they can’t help but feel sorry for these beautiful deaf people who can’t get hearing. These beautiful “Thousand Hands Guanyin”, deafness has a variety of causes, of which, the vast majority of deaf people are due to the injection of streptomycin in childhood and “an injection of deafness”, lost hearing forever. The National Molecular Epidemiological Survey of Deafness showed that 4.4% of the deaf population in China carry mitochondrial gene mutations that can cause hearing loss after the use of aminoglycosides represented by streptomycin. There is also a part of congenital deafness, which is inherent in the mother or formed at birth, such as disturbance of fetal development in the mother, resulting in underdeveloped or undeveloped inner ear; maternal illness during pregnancy with drug poisoning, birth injury, etc. In addition to congenital hearing impairment, hereditary deafness can also manifest itself in the form of delayed hearing impairment. The characteristics of delayed deafness are: people with delayed deafness often have a good language foundation; the process of delayed deafness is gradual; and delayed genetic deafness is usually genetically linked. Although late-onset deafness does not occur over a short period of time, it will still have an impact on people’s work and schooling as their hearing loss increases. Nowadays, science and technology have introduced cochlear implantation, which is a true “deaf but not dumb” procedure that allows deaf patients to return to the world of sound. So, how can cochlear implantation be best used? This can only be done with proper pre-operative hearing evaluation. First of all, cochlear implantation is a method of auditory intervention for patients with more than severe sensorineural deafness, so the first step is to conduct an audiological evaluation to understand the degree of deafness, its nature, and its impact on speech, including the following: 1. Subjective hearing test: Pure tone audiometry for adults and children who can cooperate. For children who cannot cooperate with pure tone audiometry, behavioral observation, visual reinforcement, and play audiometry may be used. 2.Objective hearing test: (1) Acoustic conductance (tympanogram and acoustic reflex); (2) Auditory brainstem evoked potentials (ABR); (3) Otoacoustic emission (OAE); (4) Multi-frequency steady-state evoked potentials (ASSR). 3. Auditory ability assessment in children 4. Auditory-speech ability test: Secondly, after the audiological examination meets the criteria for cochlear implantation, deaf patients also need to undergo imaging evaluation, including high-resolution temporal bone CT and auditory nerve MRI. CT shows whether the bilateral cochlea and internal auditory canal structures are normal. MRI of the auditory nerve can show fluid filling of the cochlea and internal auditory canal and abnormalities in the development of the auditory nerve. If necessary, a cranial MRI is added to understand any organic/progressive lesions in the brain. Again, certain psychiatric, intellectual, and behavioral assessments are needed to understand the mental development of the pediatric population and the presence of psychological disorders and behavioral abnormalities. Specifically, these include: 1) Hi-Ne learning ability test scores 2) Graflex mental development test scores 3) Autism and autism tests All of these examinations or tests are currently the main components of the preoperative evaluation required for cochlear implant candidates. In addition, one of the more important tests is the deafness genetic test. The analysis of the deafness genetic test results not only determines the mode of inheritance, calculates the risk of deafness recurrence, and provides an accurate assessment and interpretation of the risk of the disease, the risk of carriers, and the risk of recurrence in the offspring of the patient and his or her family members; but also provides a lifelong genetic service for the tested person and his or her family members. The prevention and interruption of hereditary deafness at its root through objective and accurate reproductive guidance and interventions has become an important step and means to achieve the goal of preventing deafness birth defects. With the rapid development of deafness genomic science and molecular biology techniques, deafness genetic studies and clinical diagnostic techniques have become important tools for the etiological analysis of deafness, and one can already clarify the genetic etiology or the carriage of its causative mutations in most deafness subjects in the Chinese population by testing for several common deafness genes. Modern technological advances have successfully introduced cochlear implants and deafness genetic testing, an advancement that allows deaf people to enter the world of sound sooner and hear more and more beautiful sounds.