Coughing, chest tightness, shortness of breath and dyspnea may be caused by COPD, bronchial asthma, heart disease and other reasons. 1. COPD: COPD is a lung disease characterized by irreversible airflow limitation, which is usually manifested clinically by symptoms such as chronic cough, sputum, shortness of breath after activity, chest tightness or dyspnea, which are more pronounced during acute exacerbation. 2. Bronchial asthma: bronchial asthma is a heterogeneous disease characterized by airway hyperresponsiveness, mainly manifested as episodic cough, wheezing, dyspnea, often caused by allergens, cold air and other stimuli. 3. Heart disease: such as chronic heart failure, when the cardiac volume falls, resulting in increased pulmonary stasis, it will show symptoms such as chest tightness, cough, shortness of breath, dyspnea. Cough chest tightness shortness of breath dyspnea can also be caused by other diseases, such as symptoms do not improve or aggravate, it is recommended to the regular hospital for examination, clear causes, and timely targeted treatment.