Patients with cystic solid thyroid nodules take different medications depending on the cause of the disease. For example, cystic nodules caused by iodine deficiency can be treated with iodine-containing foods and thyroxine supplements; cystic nodules formed by subacute thyroiditis can be treated with aspirin, prednisone and other medications; malignant cystic nodules of the thyroid gland are usually treated with surgery, and medication has no significant effect. 1. Iodine deficiency: Iodine deficiency can cause compensatory enlargement of the thyroid gland and the formation of cystic solid nodules in the thyroid gland. It can be treated by consuming iodine-containing foods or supplementing iodine-containing drugs such as potassium iodide, and thyroxine tablets can be supplemented when thyroid hormones are reduced due to iodine deficiency. 2. Subacute thyroiditis: In subacute thyroiditis, the follicles of the thyroid gland are destroyed and the gelatinous cells spill out, forming cystic nodules. Aspirin, ibuprofen, prednisone and other drugs can be taken to control the inflammatory reaction and relieve the patient’s pain symptoms. 3. Thyroid cancer: cystic nodules caused by cancerous transformation of thyroid cells. It is usually treated by total thyroidectomy and life-long supplementation of thyroxine tablets after surgery. Therefore, patients with cystic solid thyroid nodules should go to the hospital in time, improve the examination, clarify the cause of the formation of cystic solid nodules, and choose the appropriate treatment under the guidance of the doctor.