Cases of pediatric bedwetting are often encountered in clinical work and are briefly summarized. Enuresis is defined as bedwetting during sleep still occurring >2 times/week for more than 6 months in children over 5 years of age. It is reported that the incidence is about 4 years old 20-25%, 7 years old 5-10%, 15 years old 1-2% The main causes of primary enuresis can be the following: ① delayed development of the cerebral cortex can not inhibit the spinal cord urinary center in the post-sleep forced urethritis muscle uninhibited contraction will be discharged; ② sleep is too deep (central sleep-wake disorders): failure to wake up immediately after falling asleep when the bladder is swollen; ③ sleep antidiuretic Antidiuretic hormone (ADH) secretion is reduced; ④ genetic factors: the child’s parents or siblings have a higher incidence of enuresis Diagnosis and commonly used tests: Diagnosis of primary enuresis is based on the principle of exclusion of secondary enuresis secondary to a variety of causes of enuresis ① history: pay attention to the presence or absence of hereditary factors at the same time, there is constipation or neurological disorders that may be secondary to the neurogenic bladder. ② physical examination: for a detailed physical examination of the whole body, pay special attention to the anal sphincter muscle tone is normal with or without spina bifida perineal sensation with or without loss of sensation and lower limb activity is normal ③ laboratory tests: urine routine urine culture ④ X-ray examination: plain film to observe the presence or absence of spina bifida cystourethrocystography to observe the presence or absence of mechanical obstruction ⑤ urodynamic examination: urinary flow rate examination to observe the presence or absence of obstruction of the lower urinary tract intravesical pressure determination to observe the absence or absence of inhibition of the urinary tract. Shrinkage Treatment should do attention, full-time, cooperation, persistence, follow-up In the treatment, family regulation is very important, firstly, parents should talk with their children seriously, give encouragement, so that they can set up confidence, gradually correct the shyness, anxiety, fear and shrinkage and other emotions or behaviors, and cooperate with the treatment. Secondly, do a good job of life regulation, avoid overwork, dinner time can not be too late, soup can not be too salty, do not drink water before going to bed, do not eat juicy fruits, urinate before going to bed. Training regulation: in the past night often bedwetting time half an hour in advance with an alarm clock combined with artificial wake up, let it walk back and forth indoors, or wash your face with cold water, so that in a state of mental alertness to urinate, the purpose is also to help establish a conditioned reflex. Parents should promptly detect bedwetting and urge the child to empty the residual urine, dry the area, change underwear and dry the bed on his/her own. Parents should record the cause and frequency of bedwetting on a daily basis, mark bedwetting and non-bedwetting on the schedule, summarize once a week to find out the causes, and give encouragement when the child makes progress. During the daytime, the child should try to prolong the interval between urination gradually from every 1/2~1 hour to 3~4 hours to expand the bladder capacity. Medication: 3 months as a course of treatment, the advantage is quick effect, the disadvantage is that there are different degrees of side effects and easy to recur after stopping the drug. It is recommended to be checked in hospital before applying.