Premature ejaculation is a condition in which ejaculation occurs too early during sexual intercourse, or even before intercourse or at first intercourse, so that normal sexual intercourse is not possible. Premature ejaculation is a common symptom of men’s sexual dysfunction, mostly accompanied by spermatorrhea and impotence. The treatment of premature ejaculation requires evidence-based treatment, can not be partial to a single prescription, a single medicine is weak, generally should be in the physician’s evidence-based treatment under the use of drugs. Premature ejaculation is mostly caused by internal injuries to emotions, dampness and heat, excessive indulgence, and chronic illness. 1. Damp-heat in the liver meridian: premature ejaculation, easy to lift the penis; accompanied by bitter mouth and dry throat, chest tightness and dystocia (pain in the area of the ribs), wet and itchy scrotum, yellowish and turbid urine; red tongue, yellowish and greasy moss, and slippery and numbered pulse. The formula is gentian diarrhea liver soup. 2. Deficiency of heart and spleen: premature ejaculation, palpitation and palpitation with anxiety (violent heartbeat, panic), forgetfulness and dreaminess, poor appetite, abdominal distension and loose stools (thin and unshaped feces), fatigue (mental exhaustion, physical weakness); pale tongue, weak pulse. The formula is Gui Spleen Tang. 3. Phase Fire: premature ejaculation, easy lifting of the yang, lumbar and knee pain and weakness, heart-heat (heat in the heart of the hands and feet, and self-consciousness of the heart and chest), hot flashes and night sweating (abnormal sweating after going to sleep, but sweating stops after waking up); red tongue with little moss, and fine pulse (the pulse becomes narrower and finer, and its rate increases). The formula is Zhi Bai Di Huang Wan. 4. Kidney qi failure: premature ejaculation and spermatorrhea, loss of libido, lumbar and knee pain and weakness, long and clear urination, nocturia, whitish complexion (white color and lack of luster); pale tongue, white moss, weak pulse. Prescription: Jin Gui Ren Qi Wan. The medication should be taken under the guidance of a professional physician, and should not be taken on one’s own, so as not to cause delay in the condition.