The treatment of H. pylori is usually mainly a combination of multiple drugs, and triple or quadruple therapy is often used in clinical practice. Commonly used drugs include proton pump inhibitors such as omeprazole, H2 receptor antagonists such as cimetidine, antibiotics such as metronidazole and clarithromycin, and bismuth such as bismuth potassium citrate. The more commonly used drugs in the clinic are mainly in the following categories: 1. Proton pump inhibitors: the main role of proton pump inhibitors is to inhibit the secretion of gastric acid, and at the same time can promote the healing of the ulcer surface destroyed by Helicobacter pylori, common drugs are lansoprazole, rabeprazole and so on. 2. Antibiotics: antibiotics mainly play the role of anti-infection, common drugs are metronidazole, clarithromycin, amoxicillin and so on. 3. Bismuth: Bismuth can effectively promote the healing of the ulcer surface, protect the gastric mucosa, common drugs are bismuth potassium citrate and so on. Drugs should be used under the guidance of a doctor.