Female vulvar leukoplakia generally includes vulvar sclerosing moss and vulvar simple moss, and can be treated with glucocorticoid drugs, immunosuppressants, retinoids, sex hormone preparations and antibiotics. 1. Glucocorticoid drugs: these drugs have strong anti-inflammatory effect, can prevent further deterioration of the condition, control the condition, the more commonly used drugs are clobetasol ointment, mometasone furoate cream, trimethoprim injection and so on. 2. Immunosuppressants: these drugs can play a role in regulating the skin’s immune factors, the more commonly used drugs are tacrolimus ointment, pimecrolimus ointment and so on. 3. Retinoids: These drugs can improve the symptoms of vulvar sclerosing moss and can be used as an adjunctive drug, such as retinoic acid cream. 4. Sex hormones: These drugs are effective in relieving the symptoms of vulvovaginal sclerosing moss, and commonly used drugs include ethinyl estradiol ointment. Before choosing medication, it is important to have a doctor’s consultation and to follow the doctor’s instructions strictly.