Some premature ejaculation can be cured with treatment. Premature ejaculation needs to be treated according to the cause. The causes of premature ejaculation are often categorized into psychological and other causes that induce high sensitivity of penile sensation, and the treatment includes psychological counseling and reduction of sensitivity. For psychological causes of premature ejaculation, patients often have a wrong understanding of sexual behavior and self-guilt, resulting in physical and mental negative impact, and then fear, avoid sex. The first choice of treatment is psychological counseling, which requires close cooperation with the partner to avoid anxiety and to establish and restore normal natural responses. For patients with highly sensitive penile sensation caused by other reasons, it has been found in recent years that 5-hydroxytryptamine receptor subtypes are related to the ejaculation threshold, and some of the subtypes have low thresholds, which are easily excited and cause premature ejaculation. Can be applied through the application of condoms during sexual intercourse, or the head of the penis local application of lidocaine spray or ointment, can also be oral 5-hydroxytryptamine reabsorption inhibitors class of drugs (such as dapoxetine), all have a better therapeutic effect. In summary, if there is premature ejaculation should be timely medical consultation, follow the doctor’s prescription medication.