Acute myocardial infarction is caused by sudden occlusion of coronary arteries resulting in myocardial ischemia and hypoxia, producing a state of myocardial necrosis. Patients will have persistent angina pectoris, which is not relieved by medications, profuse sweating, a sense of frequent death, and even symptoms of shock. Once acute myocardial infarction occurs, thrombolytic therapy is required within 6 hours. Post-thrombolytic care measures include continuous cardiac monitoring, from which the basic vital characteristics of the patient, such as blood pressure, heart rate, oxygen saturation, and the number of breaths, can be understood. In addition, the patient should be monitored for bleeding from the puncture site and the hematoma, and the medication should be changed regularly. Then, coronary-dilating and anticoagulant drugs, such as aspirin and nitrates, are given. In the process of taking the drugs, it is important to observe the adverse reactions and to reduce or discontinue the drugs as soon as they occur.