The term “hormone” is not a medical term, but refers to hormone, and the so-called female hormone refers to estrogen and progesterone, normal women do not need to supplement estrogen and progesterone, but additional supplementation will lead to endocrine disruption, which will damage the body’s health. If the lack of estrogen and progesterone leads to disease, it can be supplemented by oral estradiol valerate, nil estradiol, progesterone, and so on. 1. Estradiol valerate is a natural estrogen, which can increase the level of estrogen in women, and is mostly used in the treatment of estrogen deficiency resulting in senile vaginitis, estrogen-deficient amenorrhea, menopausal syndrome, and female gonadal dysfunction, etc. Some women may experience nausea after taking it. Some women may have adverse reactions such as nausea, abdominal pain, skin rash and vaginal bleeding after taking it. 2. Nilestrol: it is a long-acting estrogen, mainly used for the treatment of estrogen deficiency caused by menopausal syndrome, senile vaginitis, and can prevent postmenopausal osteoporosis and cardiovascular disease. Adverse reactions such as breast swelling and pain, leukorrhea, nausea and bloating may occur after taking it. 3. Progesterone: For patients with luteal insufficiency and preeclampsia, progesterone or dextroprogesterone can be given. It should be noted that estrogenic drugs for pregnancy, lactation, estrogen-dependent tumors and unexplained vaginal bleeding and other groups of people are prohibited, the use of drugs need to follow the doctor’s instructions, in order to avoid serious damage to health. If there are no symptoms of estrogen deficiency, there is no need to use drugs, and unauthorized long-term use of estrogen in postmenopausal women may increase the risk of endometrial cancer.