Desensitization therapy started with hay fever, and in 1911, Dr Noon and Freeman in England were the first to start immunotherapy using laddergrass pollen. A small amount of antigen was administered to the patient, and once the time had passed, the patient’s symptoms were significantly reduced, making this treatment method desensitization therapy. Many studies later found that this treatment method could not completely desensitize the organism, so it should be called desensitization therapy. But desensitization therapy has a long history of application, so it is now collectively called desensitization therapy, and is the only etiological treatment for allergic diseases such as allergic rhinitis and asthma, which can change the course of allergic diseases, prevent the emergence of new allergenic allergens, stop allergic rhinitis from developing into asthma, and likewise stop asthma combined with allergic rhinitis from developing into total airway inflammation, and can maintain the efficacy for a longer period of time after stopping the medication. Treating allergic diseases from the root. Our hospital has many years of clinical experience in treating allergic rhinitis, dermatitis, urticaria and other allergic diseases. There are two methods of sublingual desensitization and subcutaneous injection, and the course of treatment is usually 3-5 years depending on the condition of the patient. Depending on the patient’s economic situation and a combination of factors, we choose domestic (Concordia Xinhualian Pharmaceutical Co., Ltd. costs about 1,500 yuan a year) and imported (Anda) costs about 6,000 yuan a year.