Drug allergy itching, known as medication dermatitis, and its quick itch relief varies from person to person and includes daily care and medication. Patients with drug dermatitis may have symptoms such as rash, itching and pain. The first step in treating drug dermatitis is to stop using the allergy-causing drugs, and after stopping the allergy-causing drugs, the itching symptoms can mostly subside. If the itching is not eliminated, it can be treated with loratadine, cetirizine, vitamin C, and, if necessary, the appropriate dose of prednisone. In addition, the local itching area can also be used externally with glycerine lotion, mometasone furoate cream and other drugs to stop itching. It is recommended to consult the dermatology department of the hospital as soon as possible, and the use of drugs should be carried out under the guidance of medical professionals.