Sprays for premature ejaculation are mainly topical surface anesthetics, and approval passes for drugs such as lidocaine spray and bupivacaine spray. 1. Lidocaine spray is a non-aqueous solution, a mixture that does not contain alcohol, which prevents a stinging sensation during application. Patients with primary premature ejaculation treated with lidocaine spray have increased ejaculatory latency, control, and sexual satisfaction, suggesting that there are significant benefits to both the patient and his or her partner with the use of this medication. 2. Bupivacaine spray, also a local anesthetic spray, is effective in prolonging ejaculatory latency and reducing sensitivity in patients. Adverse reactions include skin irritation, rapid heartbeat, and fainting. All of the above drugs are sprays for the treatment of premature ejaculation and are contraindicated for those who are allergic to them. Patients are not recommended to buy and use them on their own, and should use them under the guidance of a professional doctor.