In order to diagnose drug-related liver damage, physical examination, laboratory tests such as blood routine, liver biochemistry, immunological indexes, imaging examination or pathological biopsy should be performed. 1. Physical examination: visual examination to check whether the patient is accompanied by jaundice, and percussion to check whether the patient has ascites. 2. Laboratory examination: including blood routine, liver biochemistry, immunological indexes and so on. (1) Blood routine: most patients with drug-induced liver injury have no obvious changes in blood routine, and the proportion of eosinophils may be elevated in some patients with drug-induced liver injury who have allergic symptoms. (2) Liver biochemistry: Serum ALP, ALT and bilirubin are detected to evaluate liver function and distinguish the type of drug-related liver injury, whether it is hepatocellular or biliary type of liver injury. (3) Immunological indexes: in order to exclude viral hepatitis, viral markers and serum viral antibodies should be detected. (3) Imaging examination: ultrasound examination of the liver should be carried out to clarify the size of the liver, whether there is splenic involvement, whether there is fibrosis and the degree of fibrosis, and whether there is cirrhosis. 4. Pathologic examination: liver biopsy is not necessary, if the above examination still cannot confirm the diagnosis of drug-related liver damage, liver biopsy can be considered. For people who suspect drug-induced liver damage, it is recommended to go to the hospital in time to complete the above examinations and actively treat the disease once diagnosed, so as to avoid delaying the disease.