Hypogonadism is a very common phenomenon in people with diabetes, with an incidence of between 30% and 70%. The longer the duration of diabetes, the more severe the problem. Clinically, vascular dysfunction due to overall metabolism has been found to be the main cause. In terms of treatment, first of all, blood glucose should be controlled better so that it stabilizes to the standard. Once the patient develops gonadal dysfunction, an evaluation of the cause of the problem should be done. It is also important to confirm whether it is accompanied by a decrease in the level of gonadal hormones. If this is the case, then treatment should be directed towards the hormonal problem. If it can be excluded that the hormone deficiency is due to congenital development and acquired dysfunction, then the main goal of treatment is psychological counseling. Secondly, medication should be administered. If it is accompanied by hypogonadism, a small amount of hormone supplementation can be used, which is beneficial not only for the improvement of gonadal function, but also for the functioning of other organs, such as the prevention of cardiovascular disease, osteoporosis, and the control of blood glucose. Once again, you can also use drugs for blood vessels and nerves, such as vitamin B12 and vasodilating drugs, some Chinese medicines (Thrombotoxin, safflower extract, etc.) and western medicines (Calcium hydroxybenzenesulfonate, etc.) are good for establishing blood circulation and nerve nutrition, but recovery is a long process. Sildenafil-based drugs have the fastest effect, and are effective for male patients, and are also suitable for female patients. However, it should be used with caution, and in the process of using the drug, especially pay attention to the changes in blood pressure and the heart’s ability to withstand, because this kind of drug is a vasodilator drug, especially can not take nitroglycerin drugs at the same time, otherwise it will cause excessive fluctuations in blood pressure, which is very harmful to the human body.