A wart is mainly caused by the human papilloma virus infection, which is commonly known as a wart, while a mole is mainly made up of mole cells and is a completely different disease from a wart. The wart can be treated with freezing, laser or topical medication. It is best to have the mole surgically removed and then have a pathological examination to make a clear diagnosis, because a wart is not usually malignant, but a pigmented mole can easily turn into a malignant melanoma. It is recommended that moles should not be removed by freezing or laser, because they are easy to be removed uncleanly if they are shallow and easy to leave marks and scars if they are deep. If a mole has malignant changes, laser or freezing cannot be judged, so if it is a mole, it is best to operate.