Panniculodermatitis treatment drugs include topical ointment, local injection drugs, and systemic drugs. 1. Topical ointment: (1) Glucocorticoid preparations: tretinoin, betamethasone, dexamethasone and other ointments or creams can be used with anti-inflammatory effects. (2) Calcium-regulated phosphatase inhibitors: when the use of glucocorticoid preparations is ineffective, tacrolimus ointment can be considered, anti-inflammatory and anti-itch. (3) Tar-based preparations: such as bran distillate ointment, coal tar ointment, pine distillate ointment, etc., with anti-inflammatory, antipruritic, astringent and other effects. 2. Local injection of drugs: can choose tretinoin acetate injection, add lidocaine due to injection, subcutaneous injection, helps to inhibit inflammation, reduce itching symptoms. 3. Systemic medication: oral ketotifen, ebastine and other antihistamines such as symptomatic itching, and supplemented with vitamin B intranasal; neurological symptoms, the application of sedatives, such as diazepam, etc.; generalized lesions oral tretinoin tablets. It is recommended that patients with generalized neurodermatitis to the hospital, under the guidance of the doctor for treatment, the above drugs need to be used in accordance with medical advice.