Psoriasis is the common name for psoriasis, and the duration of its treatment with biologics varies from person to person, usually ranging from 1 to 12 months. Biological agent treatment of psoriasis, is the use of bioengineering technology made of antibody drugs for treatment, common drugs are enalapril, adalimumab, etc., can be more precise action on the disease-causing target, will not affect the entire immune system, has good targeting, good efficacy. However, as an emerging treatment, it is more expensive and the long-term side effects are difficult to predict. The time of treatment of psoriasis with biological agents can not be generalized, it is related to the patient’s physique, patient’s condition, drug type, treatment method and other factors, the doctor will adjust the dosage of medication and the treatment time according to the specific treatment situation, generally short-term treatment needs 1~3 months, continuous treatment needs 12 months, or even more time. At present, in addition to biological agents, the treatment of psoriasis also includes glucocorticoids, vitamin D3 derivatives, calcium-modulated phosphatase inhibitors and other localized medication, physical therapy such as phototherapy and bathing therapy, and some traditional Chinese medicine (TCM) treatments have also shown good efficacy. However, psoriasis is difficult to be cured completely, and the treatment is mainly to control the condition, itching, skin lesions and other symptoms, and reduce the occurrence of complications. It is recommended that patients with psoriasis should seek medical treatment in time, and doctors will formulate a comprehensive treatment plan according to the patient’s condition, affordability, previous treatment history, etc. Patients need to adhere to standardized treatment and avoid using medication privately, so as not to delay the condition.