Differential diagnosis of squamous epithelial verrucous hyperplasia of the vulva

  1, fluffy labia minora: also known as pseudo warts, the young women in the inner labia minora, vaginal vestibule and around the urethra, is symmetrical dense distribution of 1 to 2mm diameter white or light red papules, smooth surface, some can be fluffy, caviar or polypoid. There are no obvious conscious symptoms and occasional itching. The white acetate test is negative.  2, sebaceous gland ectopic disease: glans, foreskin or labia minora and other parts of the glans, isolated and slightly elevated, clusters or patches of yellow-white or yellowish papules, no conscious symptoms. Each papule is histologically characterized by a group of small mature sebaceous gland lobules, which surround the sebaceous ducts.   3, flat warts: the second stage of syphilis rash, for the genital area of the papule or plaque, the surface is flat and moist, can also be granular or cauliflower-shaped, dark field examination can be found syphilis spirochete, syphilis serological reaction positive.  4, Bowen-like papulosis: the lesions are gray-brown or reddish-brown flat papules, mostly multiple, round or irregular, the surface of the papules may have a velvety appearance, or mildly keratinized warts. In men, they are more likely to be found on the penis, scrotum and glans, and in women, on the labia minora and perianal area. There are usually no conscious symptoms. Histopathological examination can help identify.  5, sweat duct tumor: manifestation of small, hard solid skin color or tan papules, about a few millimeters in diameter, multiple, usually no conscious symptoms. Histopathological examination can confirm the diagnosis.  6, genital squamous cell carcinoma: seen in people over 40 years old, the damage is a lump or plaque, infiltration is obvious, hard, easy to bleed, often forming ulcers, histopathological examination can confirm the diagnosis.  7, pseudo warts: the damage is confined to the labia minora in the form of fish-egg reddish papules or fluffy changes, the surface of the lesions is smooth, the white acetate test negative, pathology without diagnostic significance of the concave hollow cells.