Whether patients with a blood uric acid level of 449 μmol/L need to take medication needs to be analyzed in conjunction with whether or not the patient has gout or whether or not there are factors such as hypertension, coronary heart disease, obesity, stroke, etc. If such conditions do not exist, then no medication is needed for the time being. Normal purine diet, non-same day two fasting blood uric acid level higher than 420 μmol / L can be diagnosed as hyperuricemia, but not all hyperuricemia need to be treated with medication, if the blood uric acid 449 μmol / L patients have already occurred more than two times the gout, should start taking uric acid-lowering drug therapy. Patients with blood uric acid 449 μmol/L should also be started on uric acid-lowering drug therapy if they have had only 1 acute attack of gout and have coexisted with dyslipidemia, stroke, cardiac insufficiency, uric acid renal stones, gouty stones, or evidence of urate deposits in the joint cavity. Patients with simple hyperuricemia who do not have any of the above mentioned conditions do not need medication yet, they need to control their uric acid level through lifestyle modification, low purine diet, drinking plenty of water, quitting smoking and restricting alcohol, and moderate exercise to avoid gouty attacks. It is recommended that patients with blood uric acid 449μmol/L should go to the Department of Rheumatology and Immunology of regular hospitals for detailed consultation and treatment as prescribed.