There are many reasons why women have vulvar itching that is serious at night: 1. It may be that women suffer from gynecological inflammation, such as bacterial, trichomonas, mycobacterial, and senile vaginitis. These diseases are infected by germs and are not treated regularly for a long time, the inflammation stimulates the vaginal mucosa causing certain damage, which also increases the secretions and causes vulvar itching, and the itching symptoms are more serious at night, also the symptoms of itching appear before and after menstruation, it is recommended that patients go to the hospital to do a guided secretion examination to confirm the diagnosis. 2, it may be that women suffer from diseases such as vulvar leukoplakia, vulvar eczema and pubic lice. These diseases can cause local papules and bumps on the vulva, whitening, atrophy and ulceration of the mucous membrane of the labia majora and minora of the vulva, and when the condition strikes, it can cause itching of the vulva, especially at night. 3. It may be an allergy to sanitary napkins, condoms and chemical fiber underwear, which can also cause symptoms of itching of the vulva, and it is recommended to use cotton sanitary napkins and underwear. In addition, there are women suffering from uremia or diabetes, when the condition is serious will appear the symptoms of vulvar itching, the specific cause should also find a physician to check.