(1) Cytomegalovirus infection is divided into congenital infection (intrauterine infection) and acquired infection; newborns with positive serum cytomegalovirus IgM and DNA within two to three weeks after birth are generally judged to have intrauterine infection. Intrauterine infections can mainly affect the baby’s hearing. Intrauterine infections tend to be problematic, while acquired infections are usually asymptomatic. (2) Cytomegalovirus infections are very common and it is sometimes difficult to distinguish between intrauterine infections or infections at birth. Hearing screening may be done and the main danger is that it affects hearing. (3) Cytomegalovirus infection will remain in the body after infection. Most of our people have this virus in their bodies. (4) Breastfeeding is not a contraindication to cytomegalovirus infection, and many people in our country are positive for cytomegalovirus DNA in breast milk. As long as the child is full term and immunocompetent, breastfeeding is allowed. (5) Cytomegalovirus treatment medications can have side effects, so treatment is limited to symptomatic infections that are restricted to those with active cytomegalovirus replication. An indicator of active replication is a positive CMV-DNA in the blood. If the hearing is normal and the blood is negative for CMV-DNA, no treatment is required. (6) There are many causes of high transaminases and jaundice, not necessarily cytomegalovirus infection. (7) Giant cell infection is mainly a primary infection that can cause problems, and reactivation of the infection can also be a problem, although it is relatively mild. (8) Regarding the issue of continuing to breastfeed the baby, some experts think not to do so, but some studies have shown that it is okay for the mother to breastfeed her baby if she is CMV-IgG-positive. The vast majority of us have this virus in our bodies, and sooner or later the baby will be infected. Surveys have found that by age 2, 60% of babies have been infected and only a very small percentage will show up as having the disease. (9) CMV-DNA in blood can tell whether the virus has replicated or not, but neither CMV-DNA nor CMV-IgG in urine can tell. CMV-Igm positive can last for 6 months, and is not a good indicator to see whether the virus is replicating. (10) A negative CMV-DNA does not require treatment. Normal hearing does not mean that the virus is not replicating. But normal hearing, your child has no other manifestations, even if CMV-DNA positive, foreign countries do not consider treatment, such as really uneasy, treatment of a course of treatment can be, but we must weigh the effectiveness of treatment and drug side effects. (11) Positive cytomegalovirus IgG antibodies and positive cytomegalovirus IgM antibodies in babies indicate that the baby is also infected, but it does not mean that the blood CMV-DNA is also positive, nor does it indicate that the virus is replicating, because cytomegalovirus IgM antibodies can last up to 6 months positive after infection or one activity in some people, while the blood CMV-DNA lasts for a short time.