1, physical examination before pregnancy: this is a checkup for both husband and wife. Especially for women who are ready to get pregnant, in addition to the routine examination of heart, liver, kidney, etc., we should also focus on the reproductive system. If you are suffering from STD, you should wait for the treatment to heal before you can get pregnant. 2, 3 months before pregnancy to take oral folic acid: taking folic acid can avoid neurological development diseases. If you don’t take folic acid in time before pregnancy, you should continue to supplement after pregnancy until 12 weeks of pregnancy. 3.Pregnancy care: extra attention should be paid to ensure regular prenatal checkups. 4.At 16-20 weeks of pregnancy, Down’s syndrome screening should be performed: this test is to extract the pregnant mother’s blood and detect the amount and concentration of various substances contained in the blood, so as to conclude that the fetus may have some medical conditions. 5, after 20 weeks of pregnancy to do amniocentesis: this test is normal for young pregnant mothers do not need to do. Studies have shown that the older the mother is, the higher the incidence of congenital dysmorphic and malformed children. It is important to note that this test has a 0.5% chance of causing a miscarriage. 6, more attention to blood sugar, blood pressure and other indicators: advanced maternal age is prone to pregnancy combined heart disease, gestational hypertension syndrome and gestational diabetes. As the blood volume in the pregnant mother’s body increases significantly compared to the non-pregnant period, the burden on the heart increases. It is likely that pregnant mothers with heart disease will have to terminate their pregnancy early because they cannot tolerate it. 7, natural childbirth is more difficult in advanced maternal age, need to be prepared in advance: the pelvis of advanced maternal age is more rigid, ligaments and soft birth tissues are less elastic, uterine contraction is correspondingly weakened, easily leading to prolonged labor, and even obstructed labor, fetal birth injury and asphyxia, the indications for cesarean section are higher, usually 90% of advanced maternal age choose cesarean section.