Meningeal irritation is a common sign in neurological physical examinations. It is mainly seen in central nervous system infections, subarachnoid hemorrhage, meningeal carcinomatosis, and other diseases, and is easily seen when the meninges and nerve roots are involved. The examiner stands on the patient’s right side, holds the patient’s occipital area with the left hand and places the right hand on the patient’s chest, flexes the patient’s neck to feel the resistance and bending. The patient’s hip and knee joints are then observed to be flexed bilaterally during flexion, and if they are, the patient has a positive Brady’s sign. The examiner then has the patient lie flat, holds the patient’s knee with the left hand, holds the patient’s ankle with the right hand, and slowly lifts the patient’s leg upward to keep the knee at 90 degrees. When the lower leg is lifted upward beyond 135 degrees and there is significant pain or resistance, it indicates a positive Kirschner’s sign. Cervical ankylosis plus Kirschner’s sign and Brønstedt’s sign constitute a complete meningeal stimulation sign.