1. Definition of adenomyosis: The presence of endometrial glands and mesenchyme in the myometrium, under the influence of hormones, results in hemorrhage p myofibrous connective tissue hyperplasia, forming diffuse lesions or limited lesions, and also forming adenomyoma. Etiology: The etiology is unclear, mainly endometrial invasion theory, others include vascular lymphatic dissemination, epithelial metaplasia and hormonal influence. Clinical manifestations: (1) dysmenorrhea: more than half of the patients have secondary dysmenorrhea with progressive worsening; (2) menstrual abnormalities: prolonged menstrual periods and irregular bleeding; (3) infertility; (4) uterine enlargement, mostly homogeneous, spherical, or raised and hard. 4. Diagnosis: Preliminary diagnosis can be made based on symptoms, pelvic examination and the following ancillary tests: (1) Ultrasound scan shows an enlarged uterus with a thickened muscular layer, more pronounced posterior wall, and an anterior shift of the endometrial line. The lesion is isoechoic or echogenically enhanced, with punctate hypoechogenicity and no clear boundary between the lesion and the surrounding area. (2) MRI shows the presence of poorly defined p-signal intensity lesions in the uterus. T2 enhancement images may have lesions with high signal intensity, and the endometrium-myometrium binding area is widened and larger than 12 mm. (3) Serum CA125 levels may be elevated in most cases. (4) Pathological examination is the gold standard for diagnosis. 5. Treatment: (1) Expectant treatment: asymptomatic p without fertility requirements can be observed. (2) Placement of the Mannheimer’s ring. (3) Surgery is the main treatment method, of which hysterectomy is the radical surgery. For young people who need to preserve their reproductive function, focal resection or wedge hysterectomy can be performed, and LUNA, PSN or uterine artery block can also be performed as an adjunct. For those who do not require fertility with increased menstrual flow, endometrial removal can be performed. (4) Medication: oral contraceptives p high potency progestin p androgen derivatives and GnRH-a four major categories …… (5) Interventional treatment (DSA). (6) Infertile patients can be treated with GnRH-a for 3-6 months and then undergo assisted conception treatment; those with limited lesions or uterine adenomyoma can be treated with surgery + GnRH-a and then undergo assisted conception treatment.