Reactive arthritis, also known as Wright’s syndrome, is a seronegative spondyloarthropathy similar to ankylosing spondylitis, and is clinically known as the ophthalmoplegia-arthritis-urethritis syndrome. It is a specific clinical type of reactive arthritis characterized by the triad of arthritis, urethritis, and conjunctivitis, often presenting as a sudden onset of acute arthritis with distinctive extra-articular cutaneous and mucocutaneous symptoms. Currently, the classification criteria of reactive arthritis proposed by Kingsley and Sieper in 1996 are used: (1) peripheral arthritis: asymmetric oligoarticular arthritis with a predominance of the lower extremities; (2) evidence of antecedent infections: (1) if clinically typical diarrhea or urethritis has been present for 4 weeks, laboratory evidence may or may not be available; (2) if there is a lack of clinical evidence of infections, there must be laboratory evidence of infections; (3) exclusion of mono- or oligoarticular joints as the cause of reactive arthritis. (3) Rule out other causes of mono- or oligoarthritis, such as other spondyloarthritis, infectious arthritis, Lyme disease, and streptococcal reactive arthritis; (4) HLA-B27 positivity, and the extra-articular manifestations of reactive arthritis (e.g., conjunctivitis, iritis, cutaneous, cardiac, and neurologic pathology), or the clinical manifestations of typical spondyloarthritis (e.g., inflammatory low back pain, alternating buttock pain, tendinitis, or iritis) are not present. or typical clinical signs of spondyloarthritis (e.g., inflammatory lower back pain, alternating hip pain, tendonitis, or iritis) are not required for a diagnosis of reactive arthritis.