The medications for the treatment of pityriasis rosea include oral medications such as ebastine, loratadine, acyclovir, and prednisone, and topical medications such as glycerite lotion and sulfur cream, which are recommended to be used under the guidance of a doctor, and their medication regimens are different for different conditions. The main symptom of pityriasis rosea is the appearance of furfuraceous scaly rose-colored macules and papules, accompanied by itching and so on. For patients with severe itching, antihistamines such as ebastine and loratadine can be taken orally as prescribed by the doctor. For pityriasis rosea caused by viral infection, antiviral drugs such as acyclovir can be used, and in severe cases, small doses of glucocorticosteroids, such as prednisone, can also be used. In addition, glycerine lotion, 5% camphor cream, sulfur cream, emollients and so on are also effective for the treatment of pityriasis rosea. Pityriasis rosea should be medicated under the guidance of a doctor, and should not be used blindly on its own, so as not to aggravate the skin damage. At the same time, during the rash should avoid eating spicy, stimulating food, avoid the use of stimulating shower gel, so as not to aggravate the condition. It is recommended that patients go to the hospital in a timely manner, under the guidance of the doctor to standardize the treatment.