Purpura nephritis hormone reduction needs to be gradual, according to the recovery of the condition gradually reduce the dose. Purpura nephritis is usually treated with medium-dose glucocorticosteroids in the clinic, taking prednisone as an example, the initial dose is 1.0~2.0mg (kg.d) early in the morning at once, and then reduce the dosage as appropriate according to the condition after 8~12 weeks, usually reduce 10% of the original dosage every 2~3 weeks after the full dose treatment, and then finally maintain it at the smallest effective dosage for another half a year or so. If the patient has a large amount of proteinuria with progressive renal function damage, glomerular crescent is greater than 50%, can be a large dose of glucocorticoid shock therapy, generally available methylprednisolone 0.5g~1.0g intravenous drip for 3~5 days, oral prednisone 1.0mg/(kg.d), 6~8 weeks after the gradual reduction, and then a small dose of oral prednisone to maintain. During the period of taking hormone, we should pay attention to observe whether there is any digestive discomfort, monitor blood sugar, blood pressure and other conditions, pay attention to gastric protection, calcium supplementation and other treatments. All of the above medications should be used under the guidance of a doctor to avoid self-medication. Patients with purpura nephritis are advised to go to regular hospitals in time for treatment under the guidance of doctors.