The success rate of IVF in China is 40%-60%. The success rate may be reduced when IVF is done at the age of 40, and fluctuates between 30%-50% depending on the local medical level. In addition to the medical level, IVF is also affected by the condition of the couple’s reproductive system, psychological factors and other aspects. In general, as age increases, reproductive function is affected in both men and women, and success rates will decrease accordingly. If a 40-year-old woman is found to have normal menstrual cycles and normal ovarian function after examination, and the quality of male sperm can meet the standards for IVF, the success rate of IVF will be relatively high at this time. In addition, the endometrium is an important place for embryo implantation. If a 40-year-old woman still maintains a good endometrial thickness, good cell division and rich blood flow, the embryo implantation rate can be increased compared to women of the same age, thus increasing the success rate of IVF. Excessive anxiety and stress in women can easily cause endocrine disorders, resulting in a decrease in follicle quality and embryo implantation success rate, thus reducing the success rate of IVF. At this time, both couples and family members should encourage each other and maintain an optimistic attitude. It is recommended to choose a professional and authoritative hospital to ensure better medical technology, which is also an important factor to improve the success rate of IVF.